[Application of functional quantum dots in cancer diagnosis and therapy: a review].

Title[Application of functional quantum dots in cancer diagnosis and therapy: a review].
Publication TypeJournal Article
Year of Publication2013
AuthorsHan S, Xia T, Li Q, Guo J, Lu P
JournalSheng wu gong cheng xue bao = Chinese journal of biotechnology
Volume29
Issue1
Pagination10-20
Date Published2013 Jan
Abstract

Quantum dots (QDs) are nanometer-sized luminescent semiconductor nanocrystals. Their unique optical properties, such as high brightness, long-term stability, simultaneous detection of multiple signals and tunable emission spectra, make them appealing as potential diagnostic and therapeutic systems in oncology. Preparing the functional QDs by modifying bio-molecules such as antibody will have potential value for cancer diagnosis and treatment. This paper summarized the recent progress of promising application of QDs in cancer diagnosis and therapy, from identifying molecular targets, to drug delivery and therapy; from limitations of toxicity issues related to QDs in living organisms to multifunctional design and development. Finally, the promising applications of QDs are also discussed.

DOI10.1002/anie.201302764
Alternate JournalSheng Wu Gong Cheng Xue Bao