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Anti-angiogenic effect of KH902 on retinal neovascularization.
|Title||Anti-angiogenic effect of KH902 on retinal neovascularization.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Wang F, Bai Y, Yu W, Han N, Huang L, Zhao M, Zhou A, Zhao M, Li X|
|Journal||Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie|
|Date Published||2013 Sep|
KH902 is a fusion protein derived from the extracellular domains of vascular endothelial growth factor (VEGF) receptors 1 and 2 and the Fc portion of immunoglobulin G1 (IgG1). Retinopathy of prematurity (ROP) is an eye disease that affects premature babies who have received intensive neonatal care, and the disorganization of retinal blood vessels may result in scarring and retinal detachment. This study was designed to examine the inhibitory effects of KH902 on mice with oxygen-induced retinopathy (OIR), one of the animal models of ROP.
|Alternate Journal||Graefes Arch. Clin. Exp. Ophthalmol.|