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ALK amplification and protein expression predict inferior prognosis in neuroblastomas.
|Title||ALK amplification and protein expression predict inferior prognosis in neuroblastomas.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Wang M, Zhou C, Sun Q, Cai R, Li Y, Wang D, Gong L|
|Journal||Experimental and molecular pathology|
|Date Published||2013 Oct|
ALK gene has been identified as a major neuroblastoma (NBL) predisposition gene. But ALK gene copy number and protein expression in ganglioneuroblastoma (GNBL) and ganglioneuroma (GN) are poorly described in the literature. Furthermore, there are controversies on the correlation between ALK protein expression and clinical outcome in NBL.
|Alternate Journal||Exp. Mol. Pathol.|