Activation of cannabinoid type 2 receptor by JWH133 protects heart against ischemia/reperfusion-induced apoptosis.

TitleActivation of cannabinoid type 2 receptor by JWH133 protects heart against ischemia/reperfusion-induced apoptosis.
Publication TypeJournal Article
Year of Publication2013
AuthorsLi Q, Wang F, Zhang Y-M, Zhou J-J, Zhang Y
JournalCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Volume31
Issue4-5
Pagination693-702
Date Published2013
Abstract

Cannabinoid type 2 (CB2) receptor agonists can protect myocardium against ischemia/reperfusion (I/R) injury although the underlying mechanism remains unclear. Here we report the antiapoptotic effect of CB2 receptor agonist, JWH133, during myocardial ischemia/reperfusion injury and potential underlying mechanisms.

DOI10.1159/000350088
Alternate JournalCell. Physiol. Biochem.