Yana Sandlers, M.Sc., Ph.D.

Yana Sandlers
Yana Sandlers
Assistant Director, Biochemical Genetics Lab

Kennedy Krieger Institute
707 N. Broadway
Baltimore, MD 21205
Phone: (443) 923-2782
Email: sandlers@kennedykrieger.org

Dr. Sandlers is assistant director of the Biochemical Genetics Laboratory at Kennedy Krieger Institute and a research associate in pediatrics at Johns Hopkins School of Medicine.


Biographical Sketch:

Dr. Sandlers received her doctorate degree in chemistry from the Technion - Israel Institute of Technology. She completed a post-doctoral fellowship in nutritional biochemistry at Case Western Reserve University. Dr. Sandlers has been with the Kennedy Krieger Institute since 2009. She is a member of the American Society of Mass Spectrometry and the Society For Inherited Metabolic Disorders.


Research Summary:

Dr. Sandlers' research is focused on understanding biochemical abnormalities underlying different metabolic conditions, especially inborn errors of metabolism and mitochondrial disorders. Dr. Sandlers research involves GC-MS, LC-MS, and tandem mass spectrometry techniques for development of novel analytical methodologies to facilitate early diagnosis of different metabolic disorders.


Research Publications: 

Bederman I., Chandramouli V., Sandlers Y., Henderson L., Cabrera M.E. (2013). Time-course of hepatic gluconeogenesis during hindlimb suspension unloading. Experimental Physiology, 98(1), 278-289.

Sandlers Y., Moser A., Hubbard W., Jones R., Kratz L. and Raymond G. (2012). Combined extraction of acyl carnitines and 26:0 lysophosphatidylcholine from dried blood spots: Prospective newborn screening for X-linked adrenoleukodystrophy. Molecular Genetics & Metabolism, 105, 416-420.

Sandlers Y., Moser A., Hubbard W. (2011). Combined screening for lysophosphatidyl cholines and acyl carnitines in dried blood spots. Molecular Genetics & Metabolism, 102(3), 250-251.

DeBarber A.E., Sandlers Y., Pappu A.S., Merkens L.S., Duell P.B., Lear S.R., Erickson S.K., Steiner R.D. (2011). Profiling Sterols in Cerebrotendinous Xanthomatosis: The Utility of Girard Derivatization and LC-ESI-MSn analysis. Journal of Chromatography, 879(17-18),1384-1392.

Denekamp C., Sandlers Y.. (2006). Electrophilicity-nucleophilicity scale also in the gas phase. Angewandte Chemie International Edition, 45(13),2093-2096.

Denekamp C., Sandlers Y.. (2005). Formation and stability of oxocarbenium ions from glycosides. Journal of Mass Spectrometry, 40(8),1055-1063.

Denekamp C., Sandlers Y.. (2005). Anomeric distinction and oxonium ion formation in acetylated glycosides. Journal of Mass Spectrometry, 40(6),765-771.