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Michael Shamblott, Ph.D.

Michael Shamblott
Michael Shamblott
Research Scientist, International Center for Spinal Cord Injury (ICSCI)

Kennedy Krieger Institute
707 N. Broadway, Suite 520
Baltimore, MD 21205
Phone: (443) 923-9227
Email: shamblott@kennedykrieger.org

Dr. Michael Shamblott is a research scientist at the International Center for Spinal Cord Injury (ICSCI) at Kennedy Krieger Institute. He is also an assistant professor with the Johns Hopkins School of Medicine, Department of Neurology, and has a joint appointment in the Johns Hopkins University Department of Chemical and Biological Engineering.

Biographical Sketch:

Dr. Shamblott earned his doctorate of philosophy in molecular and cell biology in 1995 from the University Maryland, Baltimore County (UMBC). From 1989 to 1995, while at UMBC, he worked as a research assistant in the Department of Cellular and Molecular Biology. From there, he became a post-doctoral fellow at the Johns Hopkins School of Medicine until 1999. In 2000, he was appointed as an assistant professor at the Johns Hopkins School of Medicine, Department of Gynecology and Obstetrics. Joining the International Center of Spinal Cord Injury in 2008, Dr. Shamblott became a research scientist at the Hugo W. Moser Research Institute at Kennedy Krieger Institute in the International Center for Spinal Cord Injury, switching his primary appointment to the Department of Neurology at the Johns Hopkins School of Medicine.

Dr. Shamblott has received the Pre-doctoral Fellowship Award from the Office of Naval Research and the Alfred Blalock Research Award from the Johns Hopkins University School of Medicine. In 2002, he received the Mary Tyler Moore and S. Robert Levine Clinical Career Development Award from the Juvenile Diabetes Research Foundation, and, in 2004, he was awarded the Giles W. and Elise G. Mead Foundation Award.

Research Summary:

Dr. Shamblott’s research focuses on applications of human stem and progenitor cells. He is currently involved in research to develop cell therapies for type I (juvenile) diabetes and spinal cord injury.

LINK: SciVal Experts Research Profile for Michael Shamblott

Research Publications

Pendleton, J. C., Shamblott M. J., Gary D. S., Belegu V., Hurtado A., Malone M. L., et al. (2013).  Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ. Experimental neurology. 247C, 113-121. Abstract
Jones, M. B., Chu C. H., Pendleton J. C., Betenbaugh M. J., Shiloach J., Baljinnyam B., et al. (2010).  Proliferation and pluripotency of human embryonic stem cells maintained on type I collagen.. Stem cells and development. 19(12), 1923-35. Abstract
Crane, J. L., Shamblott M. J., Axelman J., Hsu S., Levine M. A., & Germain-Lee E. L. (2009).  Imprinting status of Galpha(s), NESP55, and XLalphas in cell cultures derived from human embryonic germ cells: GNAS imprinting in human embryonic germ cells.. Clinical and translational science. 2(5), 355-60. Abstract
Niu, X., Gupta K., Yang J. T., Shamblott M. J., & Levchenko A. (2009).  Physical transfer of membrane and cytoplasmic components as a general mechanism of cell-cell communication.. Journal of cell science. 122(Pt 5), 600-10. Abstract
Hillel, A. T., Varghese S., Petsche J., Shamblott M. J., & Elisseeff J. H. (2009).  Embryonic germ cells are capable of adipogenic differentiation in vitro and in vivo.. Tissue engineering. Part A. 15(3), 479-86. Abstract
Locke, J. E., Shamblott M. J., & Cameron A. M. (2009).  Stem cells and the liver: clinical applications in transplantation.. Advances in surgery. 43, 35-51. Abstract
Locke, J. E., Sun Z., Warren D. S., Sheets T. P., Holzer H., Shamblott M. J., et al. (2008).  Generation of humanized animal livers using embryoid body-derived stem cell transplant.. Annals of surgery. 248(3), 487-93. Abstract
Zhan, X., Hill C., Brayton C. F., & Shamblott M. J. (2008).  Cells derived from human umbilical cord blood support the long-term growth of undifferentiated human embryonic stem cells.. Cloning and stem cells. 10(4), 513-22. Abstract
Patterson, E. S., Addis R. C., Shamblott M. J., & Gearhart J. D. (2008).  SOX17 directly activates Zfp202 transcription during in vitro endoderm differentiation.. Physiological genomics. 34(3), 277-84. Abstract
Clark, G. O., Yochem R. L., Axelman J., Sheets T. P., Kaczorowski D. J., & Shamblott M. J. (2007).  Glucose responsive insulin production from human embryonic germ (EG) cell derivatives.. Biochemical and biophysical research communications. 356(3), 587-93. Abstract

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