| Xiangcan Zhan, Ph.D. Research Scientist, Kennedy Krieger Institute Dr. Xiangcan Zhan is a research scientist in the International Center of Spinal Cord Injury at Kennedy Krieger Institute. |
Biographical Sketch:
Dr. Zhan received his Ph.D. degree in 1989 from the University of Adelaide, Australia. He was employed in the HortResearch Institute, New Zealand as a research scientist during 1990-2001. From 2001-2008, he was a faculty member in the Department of Gynecology and Obstetrics, School of Medicine Johns Hopkins University. He joined the International Center of Spinal Cord Injury, Kennedy Krieger Institute in 2008.
Research Summary:
Dr Zhan’s research interests are in human embryonic stem cell biology and their application in regenerative medicine. His current focuses are differentiating oligodendrocyte cells from human embryonic stem cell and using those cells for the engrafting in the spinal cord injury mouse model.
Recent Publications/Presentations:
Zhan X., Hill CM, Brayton CF, Shamblott MJ. (2008) Human Cord Blood cells derived feeder for undifferentiated growth of human embryonic stem cells. Cloning Stem Cells 10:513-522.
Gao F, Qiu B, Kar S, Zhan X., Hofmann L, Yang XM. (2006) Intravascular magnetic resonance/radiofrequency may enhance gene therapy of atherosclerotic in-stent stenosis. Academic Radiology 13:526-530.
Zhan X., Gautam Dravid, Zhaohui Y, Holy Hammond, Mike Shamblott, John Gearhart and Linzhao Cheng (2004) Functional antigen-presenting leukocytes derived from human embryonic stem cells: implications for improving transplant outcome. The Lancet 364:163-171.
Hunter H. Chen, Zhan X., Ananda Kumar, Xiangying Du, Danming Wang, Linzhao C. Cheng, Xiaoming Yang (2004) Multispectral optical imaging method for tracking vascular gene expression In Vivo. J. Biomedical Optics. 9:1223-1229.
Xiaobing Yu, Zhan X., Jenice D’Costa, Vivek M Tanavde, Zhaohui Ye, Tien Peng, Matthew T Malehorn, Xiaoming Yang, Curt I Civin and Linzhao Cheng (2003) Lentiviral vectors with dual promoters transfer high-level expression of multiple genes in human hematopoietic progenitor cells. Mol Ther 6:827-838. (Xiaobing Yu, and Zhan X. are co-first authors)
Linzhao Cheng, Holy Hammond, Zhaohui Ye, Zhan X. and Gautam Dravid (2003) Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cell 21:131-142.
Gao F, Qiu B, Kar S, Zhan X., Hofmann L, Yang XM. (2006) Intravascular magnetic resonance/radiofrequency may enhance gene therapy of atherosclerotic in-stent stenosis. Academic Radiology 13:526-530.
Zhan X., Gautam Dravid, Zhaohui Y, Holy Hammond, Mike Shamblott, John Gearhart and Linzhao Cheng (2004) Functional antigen-presenting leukocytes derived from human embryonic stem cells: implications for improving transplant outcome. The Lancet 364:163-171.
Hunter H. Chen, Zhan X., Ananda Kumar, Xiangying Du, Danming Wang, Linzhao C. Cheng, Xiaoming Yang (2004) Multispectral optical imaging method for tracking vascular gene expression In Vivo. J. Biomedical Optics. 9:1223-1229.
Xiaobing Yu, Zhan X., Jenice D’Costa, Vivek M Tanavde, Zhaohui Ye, Tien Peng, Matthew T Malehorn, Xiaoming Yang, Curt I Civin and Linzhao Cheng (2003) Lentiviral vectors with dual promoters transfer high-level expression of multiple genes in human hematopoietic progenitor cells. Mol Ther 6:827-838. (Xiaobing Yu, and Zhan X. are co-first authors)
Linzhao Cheng, Holy Hammond, Zhaohui Ye, Zhan X. and Gautam Dravid (2003) Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cell 21:131-142.
Contact Information:
Xiangcan Zhan, Ph.D.
The International Center of Spinal Cord Injury (ICSCI)
Hugo W. Moser Research Institute at Kennedy Krieger
707 N Broadway, Room 520
Baltimore, MD 21205
(map & directions)
Telephone: (443) 923-9190
Email: zhan@kennedykrieger.org
The International Center of Spinal Cord Injury (ICSCI)
Hugo W. Moser Research Institute at Kennedy Krieger
707 N Broadway, Room 520
Baltimore, MD 21205
(map & directions)
Telephone: (443) 923-9190
Email: zhan@kennedykrieger.org